Sirtuin 3 (SIRT3) is a NAD+-dependent deacetylase downregulated in aging and age-associated dis- eases such as cancer and neurodegeneration and in high-fat diet (HFD)-induced metabolic disorders. Here, we performed a small-molecule screen and identified an unexpected metabolic vulnerability.
from Google Alert - vulnerability http://ift.tt/2EW1WWP
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