Tuesday, April 17, 2018

Glutamine‐utilizing transaminases are a metabolic vulnerability of TAZ/YAP‐activated cancer cells

Abstract. The transcriptional regulators TAZ and YAP (TAZ/YAP) have emerged as pro‐tumorigenic factors that drive many oncogenic traits, including induction of cell growth, resistance to cell death, and activation of processes that promote migration and invasion. Here, we report that TAZ/YAP ...

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